The Science Behind Everderm

Stretch marks occur because an area in the skin becomes deficient in collagen and elastin. Everderm™ works to restore collagen and elastin to normal levels using two different kinds of ingredients--herbal extracts and collagen fractions.

Collagen fractions are designed to increase the skin's thickness, which makes it easier for the skin to be nourished properly. As a result, it will look younger and healthier. The skin naturally gets thinner as aging occurs, and collagen fractions can help combat this problem.
The herbs in Everderm stimulate collagen production, and also improve elasticity, normalize scars and wrinkles, and reduce inflammation. Siegesbeckia Orientalis Extract is a key ingredient that has been shown in clinical studies to improve the appearance of stretch marks dramatically within four weeks. Phyllanthus Emblica is another key ingredient that normalizes skin tones which in turn reduces the appearance of stretch marks.

We believe that Everderm is the most effective stretch mark and wrinkle cream on the market! Read more about the ingredients and compare to leading brands.

Research Indicates That It Can Work

Siegesbeckia Orientalis Extract

Siegesbeckia Orientalis Extract has been used for thousands of years to sooth inflammation and stimulate wound healing. Extracted from the herb Siegesbeckia orientalis L, this extract helps regenerate skin tissue through collagen matrix build-up.

A patent of Pierre Fabre Medicaments discusses this extract, stating that it stimulates wound healing, promotes regular tissue renewal, and restores elasticity to damaged skin with collagen fibers. Siegesbeckia Orientalis Extract has anti-inflammatory properties as well.

Research has been conducted related to how well the extract can improve stretch marks. Stretch marks result from abnormal stretching of the skin through such conditions as weight gain or pregnancy. The stretch marks affect the elastin fibers in the middle dermis, making them diminish or disappear. An effective treatment of stretch marks must address this problem, restoring normal levels of collagen and elastin fibers.

A four week research study was conducted with a crème containing 1.5% of Siegesbeckia Orientalis Extract twice a day.

Results
Length of Streaks Reduced	52.15%
Surface Smoothness Increased	13.7%
Indented Surfaces Reduced	55.4%
Length of Irregularities Reduced	52.2%

These results indicate that Siegesbeckia Orientalis Extract does in fact restructure tissue, and possesses qualities that are valuable in the treatment of stretch marks.

Emblica

Emblica is an extract from the herb Phyllanthus emblica, which has been used for centuries in India and other countries.

In studies, Emblica has demonstrated that it has powerful antioxidant properties, and remains stable and effective for over a year. (Most antioxidants such as vitamins C and E lose their effectiveness after just a few months.) Emblica has been shown to increase skin hydration and skin lipids, reduce collagenase activity, reduce erythema, and reduce inflammation. Emblica is also a skin lightener, without the toxicity issues of most commercial skin lighteners.

Biopeptide-CL

Biopeptide-CL is a synthetic protein, made up of a fragment of collagen and palmitic acid. The palmitic acid is used to make collagen more lipophillic and make it more compatible with the human skin. Developed through much research, Biopeptide-CL was the result of an effort to create a substance that would act like retinoic acid without the negative characteristics.

The reported results are as follows:

In vitro:
Increases collagen production by the fibroblasts by as much as 350%. Increases hyaluronic acid production by the fibroblasts by as much as 146%.

In vivo:
The following statistics were gathered using image analysis of volunteers who used crèmes containing a 3% concentration of Biopeptide-CL for 28 days.

Results
Surface roughness	Reduced 17%
Mean depth of wrinkles	Reduced 23%
Depth of main wrinkle	Reduced 39%
Skin thickness	Increased 4%

Palmitoyl Tetrapeptide-3

Palmitoyl Tetrapeptide-3 is a synthetic peptide that is a fragment of immunoglobulin G that has been combined with palmitic acid.